| dc.description.abstract | Peptic ulcer disease (PUD) remains a significant health concern globally, affecting an estimated 4 million individuals annually, with Helicobacter pylori (H. pylori) infections responsible for about 80% of cases. Globally, approximately 50% of the population is infected with Pylori, leading to various gastrointestinal disorders. Prevalence in Kenya H. pylori infection is also very common in Kenya. According to studies, between 70% and 80% of people are affected (Kariuki et al., 2016; Wachira et al., 2019). The western region of Kenya, Kisumu County, has a very high prevalence of H. pylori infection of up to 85% of people may be affected, according to recent studies (Ochodo et al., 2021). Despite this high prevalence, there is a notable gap in understanding the specific factors that predispose individuals infected with H. pylori to develop PUD in this particular county. This study investigated socio-economic, dietary, and environmental factors predisposing individuals with H. pylori infections to peptic ulcers among patients seeking treatment at Kisumu County Referral Hospital (KCRH).
The study applied a cross-sectional hospital-based study design, the research involved 48 participants aged 15 to 60 years. Data was analyzed using both descriptive and inferential statistics applied via SPSS version 29.0. the information was collected using structured questionnaires and stool antigen tests to confirm H. pylori infections.
The findings indicate that socio-economic factors such as low household income and limited access to health insurance significantly contribute to the high prevalence of H. pylori infections. Dietary habits, particularly the frequent consumption of spicy and processed foods, were associated with an increased risk of peptic ulcer development, while low consumption of fruits and vegetables appeared to exacerbate this risk. Environmental factors such as poor sanitation and untreated water also played a critical role in the high incidence of H. pylori infections.
The study concluded that addressing socio-economic disparities, improving dietary habits, and enhancing water quality and sanitation infrastructure are essential to reducing the burden of H. pylori-related peptic ulcer disease in Kisumu County. Recommendations include public health interventions focused on education and policy initiatives aimed at improving living conditions, healthcare access, and hygiene practices. Further research is recommended to explore the long-term effects of these factors and develop more targeted strategies for prevention and management. | en_US |
